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ADAMTS13

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Hematology-Oncology

Recombinant ADAMTS13 Therapy Demonstrates Superior Efficacy and Safety Over Plasma-Based Therapy in Congenital Thrombotic Thrombocytopenic Purpura: Final Phase 3 Trial Results

Final phase 3 trial analysis confirms recombinant ADAMTS13 (rADAMTS13) provides effective prophylaxis with fewer acute and subacute TTP events and better safety than plasma-based therapy in congenital TTP patients.

Sep 28, 2026
Hematology-Oncology

Long-term Outcomes in Congenital TTP: Registry Data Show Prophylactic Plasma Reduces Clinical Events but Symptoms and Product Burden Persist

UK registry follow-up of 104 congenital TTP patients shows regular plasma prophylaxis lowers acute episodes and end‑organ events, but residual symptoms and plasma-related issues drive many patients to recombinant ADAMTS13.

Nov 15, 2025

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