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Evolving GVHD Prophylaxis in AlloHSCT: Insights from a Large Real-World Spanish Cohort
Hematology-OncologyGVHD prophylaxisAlloHSCT

Evolving GVHD Prophylaxis in AlloHSCT: Insights from a Large Real-World Spanish Cohort

By MedXY|Sep 22, 2026

A large Spanish study reveals the shifting landscape of GVHD prophylaxis in alloHSCT, highlighting widespread post-transplant cyclophosphamide use and its impact on acute and chronic GVHD incidence and survival outcomes.

Isolated HLA‑DQB1 Mismatch and Donor Age Do Not Worsen Survival After Unrelated Donor HCT with Post‑Transplant Cyclophosphamide: A Single‑Center Analysis
Hematology-Oncologyacute GVHDpost‑transplant cyclophosphamide

Isolated HLA‑DQB1 Mismatch and Donor Age Do Not Worsen Survival After Unrelated Donor HCT with Post‑Transplant Cyclophosphamide: A Single‑Center Analysis

By MedXY|Nov 12, 2025

A single‑center retrospective study of 988 unrelated donor HCTs with PTCy found no significant differences in survival or relapse for isolated HLA‑DQB1 mismatch, 7/8 mismatches, or older donor age; 7/8 mismatch increased severe acute GVHD a

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