2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria

Separately accumulates clinical and laboratory domain scores for APS classification.

Select the single best-matching option for each item; the legacy page already merges some microvascular items by highest weight.

APS Classification Criteria Items

D1. Large Vessel (Venous Thromboembolism, VTE)

D2. Large Vessel (Arterial Thrombosis, AT)

Livedo Reticularis (Examination)

Livedoid Vasculopathy

Acute/Chronic aPL Nephropathy

Pulmonary Hemorrhage

Myocardial Disease

Adrenal Hemorrhage

≥3 Consecutive Pre-embryonic/Early Fetal Deaths

Fetal Death at 16–33 Weeks of Gestation

Severe Preeclampsia or Placental Insufficiency Before 34 Weeks of Gestation

Severe Preeclampsia and Severe Placental Insufficiency Before 34 Weeks of Gestation

D5. Heart Valve Involvement

D6. Thrombocytopenia

D7. LAC

D8. aCL/aβ2-GPI

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Important Notice

This resource is intended for educational purposes only and is intended for US healthcare professionals. Healthcare professionals should use independent medical judgment. All decisions regarding patient care must be handled by a healthcare professional and be made based on the unique needs of each patient.